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Typhoid Mary Typhoid Mary
by The Ovi Team
2018-03-27 05:36:37
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March 27th 1915; Typhoid Mary, the first healthy carrier of disease ever identified in the United States, is put in quarantine, where she would remain for the rest of her life.

Mary Mallon (September 23, 1869 – November 11, 1938), also known as Typhoid Mary, was the first person in the United States identified as a healthy carrier of the pathogen associated with typhoid fever. She was presumed to have infected some 53 people, three of whom died, over the course of her career as a cook. She was forcibly quarantined twice by public health authorities, and died after nearly three decades altogether in quarantine.

typhoid01_400Mary Mallon was born in 1869 in Cookstown, County Tyrone, Ireland, UK (now Northern Ireland). She immigrated to the United States in 1884. From 1900 to 1907 she worked as a cook in the New York City area.

In 1900, she had been working in a house in Mamaroneck, New York, for under two weeks when the residents developed typhoid fever. She moved to Manhattan in 1901, and members of the family for whom she worked developed fevers and diarrhea and the laundress died. She then went to work for a lawyer until seven of the eight household members developed typhoid; Mary spent months helping to care for the people she made sick, but her care further spread the disease through the household. In 1906, she took a position in Oyster Bay, Long Island. Within two weeks, six of eleven family members were hospitalized with typhoid. She changed employment again, and similar occurred in three more households.

When typhoid researcher George Soper approached Mallon about her possible role spreading typhoid, she adamantly rejected his request for urine and stool samples. Soper left and later published the report in June, 1907, in the Journal of the American Medical Association. On his next contact with her, he brought a doctor with him, but was turned away again. Mallon's denials that she was a carrier were based in part on the diagnosis of a reputable chemist who had found her to not harbor the bacteria. Moreover, when Soper first told her she was a carrier, the concept of pathogen's health carrier state was little known. Further, class prejudice and prejudice towards the Irish were strong in the period, as was the belief that slum-dwelling immigrants were a major cause of epidemics. During a later encounter in the hospital, he told Mary that he would write a book about her and give her all the royalties; she angrily rejected his proposal and locked herself in the bathroom until he left.

The New York City Health Department sent Dr. Sara Josephine Baker to talk to Mary, but "by that time she was convinced that the law was only persecuting her when she had done nothing wrong." A few days later, Baker arrived at Mary's workplace with several police officers who took her into custody. The New York City health inspector determined her to be a carrier. Under sections 1169 and 1170 of the Greater New York Charter, Mallon was held in isolation for three years at a clinic located on North Brother Island.

It is believed that individuals can develop typhoid fever after ingesting food or water contaminated during handling by a human carrier. The human carrier is usually a healthy person who has survived a previous episode of typhoid fever yet who continues to shed the associated bacteria, Salmonella typhi, in feces and urine. It takes vigorous scrubbing and thorough disinfection with soap and hot water to remove the bacteria from the hands.

Eventually, the New York State Commissioner of Health, Eugene H. Porter, M.D., decided that disease carriers would no longer be held in isolation. Mallon could be freed if she agreed to abandon working as a cook and to take reasonable steps to prevent transmitting typhoid to others. On February 19, 1910, Mallon agreed that she "[was] prepared to change her occupation (that of cook), and would give assurance by affidavit that she would upon her release take such hygienic precautions as would protect those with whom she came in contact, from infection". She was released from quarantine and returned to the mainland.
 
She had been given a job as a laundress, which paid lower wages, however. Mallon adopted the pseudonym Mary Brown, returned to her previous occupation, and in 1915 was believed to have infected 25 people, resulting in one death, while working as a cook at New York's Sloane Hospital for Women. Public-health authorities again found and arrested Mallon, returned to quarantine on the island on March 27, 1915. Mallon was confined there for the remainder of her life. She became something of a minor celebrity, and was interviewed by journalists, forbidden to accept even a glass of water from her. Later, she was allowed to work as a technician in the island's laboratory.

Mallon spent the rest of her life in quarantine. Six years before her death, she was paralyzed by a stroke. On November 11, 1938, aged 69, she died of pneumonia. An autopsy found evidence of live typhoid bacteria in her gallbladder. It is possible that she was born with the infection, as her mother had typhoid fever during her pregnancy. Her body was cremated, and the ashes were buried at Saint Raymond's Cemetery in the Bronx.

Mallon was the first healthy typhoid carrier to be identified by medical science, and their guidelines for handling such. Some difficulties surrounding her case stemmed from Mallon's vehement denial of her possible role, as she refused to acknowledge any connection between her working as a cook and the typhoid cases. Mallon maintained that she was perfectly healthy, had never had typhoid fever, and could not be the source. Public-health authorities determined that permanent quarantine was the only way to prevent Mallon from causing significant future typhoid outbreaks.

Other healthy typhoid carriers identified in the first quarter of the 20th century include Tony Labella, an Italian immigrant, presumed to have caused over 100 cases (with five deaths); an Adirondack guide dubbed Typhoid John, presumed to have infected 36 people (with two deaths); and Alphonse Cotils, a restaurateur and bakery owner.
 
Today, Typhoid Mary is a generic term for a healthy carrier of a noted pathogen, especially one who refuses to cooperate with health authorities to minimize the risk of infection. The term is also applied to computer users who spread malicious computer software by their naïveté and neglect (or outright refusal) to use security software against the malware. See also "Typhoid adware".


    
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Leah Sellers2013-03-28 04:32:57
Well done, Ovi Team ! Good paradoxical analogy and informational commentary.

Denial is a great and determined Carrier of many Dis-eases.


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